Bonus clues for the puzzle: help for the desperate.

20 across: Asian-American comedienne who, with W, would make a breed of dog--
or a meal for one: Margaret CHO(W)

5 down: Cause of bad medical problems for women, starting despair. DES(pair)

The trick is to get a couple three entries and work from there.
Believe it or not I try to make these fairly easy.
As ever, cryptics are, well, cryptic. Generally terms like twisted or crazy mean the words,
or portions of them, are rearranged to make the answer. When something is in something,
it probably is, right there before your eyes. Sounds or we hear can mean a homonym.

-The Troll

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